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The only trick to this is to make sure the correct dosages are prescribed via a reputable conversion chart. Conversion from Parenteral Methadone to Oral Methadone: -Use a conversion ratio of 2:1 for oral to parenteral (e.g., oral methadone 10 mg to parenteral methadone 5 mg) TITRATION and MAINTENANCE: -Titrate to a dose that provides adequate analgesia and minimizes adverse reactions; dose adjustments should be no sooner than every 1 to 2 days (manufacturer); preferably no more than once a week (Institute for Safe Medical Practices (ISMP)). -Breakthrough Pain: If the level of pain increases after dose stabilization, attempt to identify the source before increasing dose; rescue medication with appropriate immediate-release analgesia may be helpful. As with any prescription medication, it is not suggested that you miss a dose.

For more specific information, consult with your doctor or local pharmacist for guidance based on your health status and current medications, particularly before taking any action. Overdosage & Contraindications OVERDOSE Signs And Symptoms Serious overdosage of methadone is characterized by respiratory depression (a decrease in respiratory rate and/or tidal volume, Cheyne-Stokes respiration, cyanosis), extreme somnolence progressing to stupor or coma, maximally constricted pupils, skeletal-muscle flaccidity, cold and clammy skin, and sometimes, bradycardia and hypotension.

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The methadone abstinence syndrome, although qualitatively similar to that of morphine, differs in that the onset is slower, the course is more prolonged, and the symptoms are less severe. 3 doctors agreed: Look them up?: Although methadone clinics are not the most commonly advertised entities on TV or radio I am sure you can Google them via the Internet and I am sure you will find something in your area.

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Elimination of methadone was significantly changed in pregnancy. Click on the city, town, or area you choose in order to be taken to the next page.

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Drug use and abuse: A comprehensive introduction (8th ed.). Lowest, Average and Highest Dosage The maximum safe maintenance dosage is between 60-120 mg. As with any prescription medication, it is not suggested that you miss a dose. If used correctly, methadone can be a very helpful h.r.t. but rarely does it work out that way. Both methadone abuse and lawfully prescribed use will eventually lead to dependence. I wouldn't be afraid to tell him the patches aren't working, and that you think the dosage is to low, especially if the conversion charts "back you up". just don't "demand"a dosage increase, let the doctor be the doctor.

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