Methadone Clinic Northfield MN
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Call our free and confidential helpline Call Now: (888)-459-5511 Table of contents: About Methadone Dosage in General Patients who are beginning to take Methadone should be given a low dosage on their first day. Keep the medication in a place where others cannot get to it. The findings from a study at the University of Maine suggest that prenatal exposure to methadone is not always harmful to the baby if the therapy is well-managed.
In severe overdosage, particularly by the intravenous route, apnea, circulatory collapse, cardiac arrest, and death may occur. Your chances of having a deadly overdose are greatly increased if you are also taking any other opioid narcotics such as Oxycontin or Hydrocodone. These factors, combined with sedation, have been linked to the causation of extensive dental damage.[31][32] Overdose[edit] Most people who have overdosed on methadone may show some of the following symptoms: Miosis (constricted pupils)[33] Vomiting[34] Hypoventilation (breathing that is too slow/shallow)[33] Drowsiness,[33] sleepiness, disorientation, sedation, unresponsiveness Skin that is cool, clammy (damp), and pale[33] Limp muscles,[33] trouble staying awake, nausea Unconsciousness[33] and coma[33] Death[34] The respiratory depression of an overdose can be treated with naloxone.[30] Naloxone is preferred to the newer, longer acting antagonist naltrexone. The complexities associated with Methadone dosing can contribute to cases of overdose. Published animal data have reported increased neonatal mortality in the offspring of male rats that were treated with methadone prior to mating.
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Onset of withdrawal symptoms in infants is usually in the first days after birth. Louis, people react differently to methadone depending on their genetic makeup.
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These problems are more likely to occur when methadone is first started or in people who were not taking other opioid pain medications. Oral: Day 1: Administer initial dose under supervision when symptoms of withdrawal are present. -Initial dose: 20 to 30 mg orally; an additional 5 to 10 mg may be given orally after 2 to 4 hours if withdrawal symptoms have not been suppressed or if symptoms reappear. -Maximum initial dose: 30 mg -Maximum day 1 dose: 40 mg -Adjust dose over the first week based on control of withdrawal symptoms at 2 to 4 hours after dosing; titrate carefully as methadone levels will accumulate over the first several days of dosing. Itʼs also possible that your computer has been infected with a Spambot virus thatʼs using your computer to gather information. However, there is usually a waiting list due to limited funding. Some clinics also offer short- or long-term detoxification services to their patients using methadone. Warnings & Precautions WARNINGS Methadone hydrochloride oral concentrate is for oral administration only.
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Opioid rotation may allow for a lower equivalent dose, and hence fewer side effects may be encountered to achieve the desired effect. The complexities associated with methadone dosing can contribute to cases of iatrogenic overdose, particularly during treatment initiation and dose titration. In addition, parenteral drug abuse is commonly associated with transmission of infectious disease such as hepatitis and HIV. Clinics require attendance at counseling groups as well as individual counseling contacts. Methadone can slow or stop your breathing, and may be habit-forming. It also depends on how long the person has been using the drug(s) and the method (i.e. oral, inhaled, or injected).[16][17] In addition, enrollment in methadone maintenance has the potential to reduce the transmission of infectious diseases associated with opiate injection, such as hepatitis B and C, and/or HIV.[16] The principal goals of methadone maintenance are to relieve opioid cravings, suppress the abstinence syndrome, and block the euphoric effects associated with opioids. Methadone can be used either as a pain reliever or as part of drug addiction detoxification and maintenance programs. Pediatric The pharmacokinetics of methadone have not been evaluated in the pediatric population.
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