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Particular vigilance is necessary during treatment initiation, during conversion from one opioid to another, and during dos e titration. Besides weakened respiratory and cardiac functions, methadone users may suffer from the following long-term medical conditions or disorders affecting various other major organs and systems of the body: Whole Body: headaches, weakness, and water retention Central Nervous System: confusion, disorientation, euphoria, depression and listlessness, sleep disturbances Endocrinal System: hypogonadism or low testosterone level, a condition that impairs growth and development in males during puberty Gastrointestinal System: abdominal pain, constipation, dry mouth Metabolic System: low potassium or magnesium levels, weight gain Blood: low platelet count that causes the blood to clot slowly after an injury, bruising, internal bleeding Kidneys: urine retention, difficulty urinating Reproductive System: reduced sexual drive, reduced sperm production, abnormal absence of menstruation in women Skin: rashes, hives, severe itching that can lead to sores Not all methadone users exhibit the adverse effects of the drugs to the same degree. Mild withdrawal symptoms that you may experience during methadone maintenance treatment include the following: Anxiety or depression Fatigue Insomnia Hot flashes Muscle pains Nausea Restlessness Cravings for drugs If these symptoms of withdrawal continue beyond the first seven days of treatment, your methadone dosage may be too low.
The potential risks of methadone should be weighed against the substantial morbidity and mortality associated with untreated opioid addiction. And what could cause it? ## I'm not sure, but it makes me wonder if perhaps they didn't mix it properly.
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A: Methadone is a narcotic analgesic or pain reliever, similar to morphine. Methadone is a slow acting opiod and takes a while to kick in no matter how you take it. All forms of methadone hydrochloride are soluble in water.
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Long-term use of narcotic pain relievers can lead to tolerance. NMDA antagonists such as dextromethorphan (DXM), ketamine (a dissociative anaesthetic), tiletamine (a veterinary anaesthetic) and ibogaine (from the African tree Tabernanthe iboga) are being studied for their role in decreasing the development of tolerance to opioids and as possible for eliminating addiction/tolerance/withdrawal, possibly by disrupting memory circuitry.
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Most counties around the country have such programs. Opiate addiction can lead to a number of consequences include health related problems, legal troubles, financial distress and potentially death. Your browser may also contain add-ons that send automated requests to our search engine. The major hazards of methadone are respiratory depression and, to a lesser degree, systemic hypotension. The physician should not confuse such symptoms with those of narcotic abstinence and should not attempt to treat anxiety by increasing the dose of methadone. Other reported clinical experience has not identified differences in responses between elderly and younger patients.
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