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363 mg is a very high dose, but like the other answerer, it depends on the person, and why they're on that dose in the first place. Methadone clinics operate as any other addiction medical facility.

Methadone Side Effects Despite the many benefits of methadone treatment, there are side effects that could come into playing during use. More information and referrals can be obtained through the following websites: SAMHSA’s Substance Abuse Treatment Facility Locator at 1-800-662-HELP (4357) or . Conversion from Parenteral Methadone to Oral Methadone: -Use a conversion ratio of 2:1 for oral to parenteral (e.g., oral methadone 10 mg to parenteral methadone 5 mg) TITRATION and MAINTENANCE: -Titrate to a dose that provides adequate analgesia and minimizes adverse reactions; dose adjustments should be no sooner than every 1 to 2 days (manufacturer); preferably no more than once a week (Institute for Safe Medical Practices (ISMP)). -Breakthrough Pain: If the level of pain increases after dose stabilization, attempt to identify the source before increasing dose; rescue medication with appropriate immediate-release analgesia may be helpful. I did 2 mg's a week from 80 mg's to 30, then did 1 mg a week until I was off methadone completely and I was very comfortable overall. Edema or fluid build-up can occur with methadone. See also: Dosage Information (in more detail) What happens if I miss a dose?

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Consumers told the review team they felt "utterly controlled" by CMP and some couldn't sleep the night before an appointment through fear they would be kicked off to face a withdrawal accepted to be worse then heroin. Mutagenesis There are several published reports on the potential genetic toxicity of methadone. Otherwise, if not done with patient and or clinic knowledge, this would be a federal offense, altering a scheduled substance. ... Patients should be apprised of the high risk of relapse to illicit drug use associated with discontinuation of methadone maintenance treatment. Gennadiy Onishchenko, Chief Sanitary Inspector, claimed in 2008 that health officials are not convinced of the treatment's efficacy. Itʼs also possible that your computer has been infected with a Spambot virus thatʼs using your computer to gather information.

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Does Methadone HCL and liquid methadone the same on drug test? Itchiness, Hives, and Seizures Itchiness, hives, and seizures are indications of a dangerous allergic response to methadone. I also breast fed him and that helps the baby as well.

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Other side effects with methadone include abdominal pain, loss of appetite, constipation, dry mouth and tongue swelling. Methadone can cause slow or shallow breathing and dangerous changes in heartbeat that may not be felt by the patient." The advisory urged that physicians use caution when prescribing methadone to people who are not used to the drug and that people take the drug exactly as directed.[23] Adverse effects of methadone include:[citation needed] Sedation Diarrhea[24] or constipation[24][25] Flushing[25] Perspiration[25] and sweating[25] Heat intolerance Dizziness[24][26][27] or fainting[24][26][27] Weakness[25] Chronic fatigue, sleepiness[25] and exhaustion Sleep problems such as drowsiness,[24] trouble falling asleep (Insomnia),[25][26] and trouble staying asleep[25] Constricted pupils Dry mouth[24][25] Nausea[24][25] and vomiting[24][25] Low blood pressure Hallucinations[24][26] or confusion[24][26] Headache[25] Heart problems such as chest pain[24][26] or fast/pounding heartbeat[24][26][27] Abnormal heart rhythms[27][28] Respiratory problems such as trouble breathing,[24][26] slow or shallow breathing (hypoventilation),[24][26] light-headedness,[24][26][27] or fainting[24][26] Loss of appetite,[24][25] and in extreme cases anorexia Weight gain[25] Memory loss Stomach pains[25] Itching Difficulty urinating[25] Swelling of the hands, arms, feet, and legs[25] Feeling restless[24] or agitated Mood changes,[25] euphoria, disorientation Nervousness[24] or anxiety[24][26] Blurred vision[25] Decreased libido,[24][25] missed menstrual periods,[25] difficulty in reaching orgasm,[24] or impotence[24][25] Skin rash Seizures Central sleep apnea Withdrawal symptoms[edit] Physical symptoms[citation needed] Lightheadedness[29] Tearing of the eyes[29][30] Mydriasis (dilated pupils)[29] Photophobia (sensitivity to light) Hyperventilation syndrome (breathing that is too fast/deep) Runny nose[30] Yawning Sneezing[30] Nausea,[29][30] vomiting,[29][30] and diarrhea[29] Fever[30] Sweating[29] Chills[30] Tremors[29][30] Akathisia (restlessness) Tachycardia (fast heartbeat)[30] Aches[29] and pains, often in the joints or legs Elevated pain sensitivity Blood pressure that is too high (hypertension, may cause stroke) Cognitive symptoms[citation needed] Suicidal ideation Susceptibility to cravings[29] Depression[29] Spontaneous orgasm Prolonged insomnia Delirium Auditory hallucinations Visual hallucinations Increased perception of odors (olfaction), real or imagined Marked decrease or increase in sex drive Agitation Anxiety[29] Panic disorder Nervousness[29] Paranoia Delusions Apathy Anorexia (symptom) Methadone withdrawal symptoms are reported as being significantly more protracted than withdrawal from opioids with shorter half-lives. XML that has been specially designed to handle such requests. Research on methadone’s potency, such as a study in Clinical Pharmacology and Therapeutics, has discovered that snorting a powered version of the substance can result in a rapid high with opioid-like effects. Read more 1 doctor agreed: 2 2 Could i go to a Suboxone clinic for heroin addiction? More expensive but less strict guidelines to follow. Hypotensive Effect The administration of methadone may result in severe hypotension in patients whose ability to maintain normal blood pressure is compromised (e.g., severe volume depletion). Note: the oral solution should never be injected directly into the blood stream. That means it does have the potential to be harmful, but this drug usually does more good than harm to the thousands of people who take it.

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