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Note: if you have missed three doses in a row, call your doctor or contact your methadone clinic for advice on what to do next. 1% to 1%): Antidiuretic effect[Ref] Hematologic Frequency not reported: Reversible thrombocytopenia, lymphocytosis[Ref] Reversible thrombocytopenia has been described in opioid addicts with chronic hepatitis.[Ref] General The major adverse reaction of this drug is respiratory depression; to a lesser degree, systemic hypotension, respiratory arrest, shock, cardiac arrest, and death have occurred. Clinics require attendance at counseling groups as well as individual counseling contacts. Read More I tapered down to 160mgs of methadone in the end, I would take 600-800mgs of morphine to feel good enough.

Yes you can smoke a methadone pill, BUT from experience, it is a complete waste. It can vary depending on how the pharmacy mixes the methadone solution but there are usually 10mg of methadone per ml. Abuse of methadone poses a risk of overdose and death.

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Some data also indicate that methadone acts as an antagonist at the N-methyl-D-aspartate (NMDA) receptor. Tell your health-care provider about any negative side effects from prescription drugs. Is methadone better? ?: I can't tell you because i don't know you but even if i knew you, it depends.

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There are no accurate charts that tell you if you take 50mg of Methadone that will equal 60 mgs of Morphine. Methadone tested negative in tests for chromosome breakage and disjunction and sex-linked recessive lethal gene mutations in germ cells of Drosophila using feeding and injection procedures. Methadone reduction, called detoxification, are suitable for persons who wish to completely stop using drugs. Desipramine PBlood levels of desipramine have increased with concurrent methadone administration. Pregnancy Teratogenic Effects Pregnancy Category C There are no controlled studies of methadone use in pregnant women that can be used to establish safety. Long-term use of narcotic pain relievers can lead to tolerance.

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Derek Dore, PharmD Q: Does methadone cause serious problems with constipation? Finding a clinic (and the best clinic for your needs at that) is usually the next step which can often be time consuming, confusing, and difficult. Everyone around an individual who is addicted to opiates suffers including the friends and family members, children, co-workers and employees, classmates and fellow student body, & the community. Over the past 30 years, qualified treatment professionals have used a medication called methadone to help tens of thousands of addicted individuals transcend their dependence upon heroin, Vicodin, OxyContin and other opiates in a safe and successful manner. Oral: Day 1: Administer initial dose under supervision when symptoms of withdrawal are present. -Initial dose: 20 to 30 mg orally; an additional 5 to 10 mg may be given orally after 2 to 4 hours if withdrawal symptoms have not been suppressed or if symptoms reappear. -Maximum initial dose: 30 mg -Maximum day 1 dose: 40 mg -Adjust dose over the first week based on control of withdrawal symptoms at 2 to 4 hours after dosing; titrate carefully as methadone levels will accumulate over the first several days of dosing. If a physically dependent patient abruptly discontinues use of methadone, or the dose of methadone does not adequately “cover” the patient, an opioid abstinence or withdrawal syndrome may develop and is characterized by some or all of the following: restlessness, lacrimation, rhinorrhea, yawning, perspiration, chills, myalgia, and mydriasis. Also like you i have a had a few back surgeries so the pain can get intense at times...

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